
How SIGNIFICANT?
Breaking Bad Season 2, Episode 10

Well, you've lived with
your SIGNIFICANT other for some time.
The Big Bang Theory Season 10, Episode 4

Twenty thousand data runs
and no statistically SIGNIFICANT results.
The Big Bang Theory Season 2, Episode 13

I hear you owe that boy a SIGNIFICANT debt.
Game of Thrones Season 3, Episode 3

with his SIGNIFICANT other.
The Big Bang Theory Season 7, Episode 5